Theophyllinylmethyldioxolane derivatives, methods for their preparation and pharmaceutical compositions containing them
US4378359A · kind A · utility
9Cited by
3References
12Claims
0Family size
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Inventors
Key dates
| Filing date | Apr 6, 1981 |
| Grant date | Mar 29, 1983 |
| Priority date | — |
| Expiry date | Apr 6, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P11/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the following general formula ##STR1## wherein: X and Y are different from each other and represent --CH.sub.2 -- or an oxygen atom; R represents a radical selected from hydroxy, bromo, acetoxy, pyrrolidino, morpholino, piperazino and piperazino substituted at the position 4 by a carbethoxy, benzyl, phenyl, halophenyl, methoxyphenyl or trifluoromethylphenyl group, or when X is --CH.sub.2 -- and Y is an oxygen atom, R may represent also chloro; methods for their preparation; pharmaceutical compositions containing them. The compounds possess a remarkable antitussive activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.