Patent · US Expired

Thrombin inhibitor and preparation and use thereof

US4379142A · kind A · utility

6Cited by

1References

6Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Hans Port · Weilheim in Oberbayern, DE
Jurgen Schrenk · Weilheim, DE
Peter Wunderwald · Haunshofen, DE

Key dates

Filing date	Oct 8, 1981
Grant date	Apr 5, 1983
Priority date	—
Expiry date	Oct 8, 2001

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/831
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Thrombin inhibitor comprising a glycoprotein of a molecular weight of 68,000 to 69,000 Dalton and an isoelectric point of pH 4.5, and is further characterized in that it inhibits thrombin in the presence of dextran sulfate at least twice as strongly as in the presence of heparin, differs immunologically from antithrombin III, and does not inhibit factor Xa, plasmin and trypsin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.