Dosage for coadministering drug and percutaneous absorption enhancer
US4379454A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 17, 1981 |
| Grant date | Apr 12, 1983 |
| Priority date | — |
| Expiry date | Feb 17, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/7084
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A dosage form that coadministers a drug and a percutaneous absorption enhancer to a defined area of the skin. The dosage form comprises a body that contains supplies of drug and enhancer and has a basal surface that contacts the area of skin and transmits the drug and enhancer to the area for absorption thereby. The drug is provided to the basal surface at a rate at least as great as the rate at which the skin is able to absorb the drug whereas the enhancer is via a rate controlling means at a substantially constant rate that increases the permeability of the treated area of skin to the drug to a level at which the drug is absorbed at a therapeutically effective rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.