Patent · US Expired

Phenylalanylarginine derivatives, process for producing same and method for measuring activity of enzymes using same

US4379764A · kind A · utility

4Cited by
4References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 9, 1981
Grant dateApr 12, 1983
Priority date
Expiry dateSep 9, 2001

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A phenylalanylarginine derivative represented by the formula, ##STR1## wherein R.sub.1 represents hydrogen or an amino-protecting group; R.sub.2 and R.sub.3 represent hydrogen or guanidino-protecting groups; R.sub.4 represents naphthyl. The above compound is useful as an excellent substrate for various enzymes, such as trypsin, plasmin, kallikrein, urokinase, Cl-esterase and the like. Accordingly, the activity of enzymes can be measured by use of said compound as a substrate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.