Molecular separation column and use thereof

US4384957A · kind A · utility

Assignee

• AMF GmbH · US

Inventors

• Alvin L. Crowder, III · Cromwell, US
• Nils Dailey · Wallingford, US
• Joseph V. Fiore · Fairfield, US
• Kenneth C. Hou · Glastonbury, US
• Paul J. Marinaccio · East Orleans, US
• Eugene A. Ostreicher · Farmington, US

Key dates

• Filing date: Jul 28, 1981
• Grant date: May 24, 1983
• Expiry date: Jul 28, 2001

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/527
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A molecular separation chromotography column for effecting the differential distribution, between two phases, of the components of a sample flowing therethrough. The column contains a substantially homogeneous solid stationary phase which comprises a porous matrix of fiber having particulate immobilized therein, wherein at least one of said fiber or particulate is effective for molecular separation. The column is characterized by a reduced pressure drop, increased axial dispersion, more uniform peak shapes and better separations at high sample loading.