.beta.-Lactam antibiotics and their medicinal use

US4386089A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hans-Bodo Konig
• Karl G. Metzger · Wuppertal, DE
• Michael Preiss · Leinfelden, DE

Key dates

• Filing date: Jun 24, 1981
• Grant date: May 31, 1983
• Expiry date: Jun 24, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D499/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

.beta.-Lactam compounds of the formula ##STR1## in which B denotes an optionally substituted heterocyclic 5-membered or 6-membered ring or an optionally substituted phenyl ring, PA1 Z denotes a hydrogen atom or a C.sub.1 to C.sub.4 alkoxy group, ##STR2## Y, E.sub.1 and E.sub.2 independently of one another denote a divalent organic radical and PA1 R.sub.1, R.sub.2, R.sub.3 and R.sub.4 independently of one another denote a hydrogen atom or an alkyl, alkenyl, alkinyl, alkadienyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, aryl or heterocyclyl radical, it also being possible for the above-mentioned radicals, with the exception of hydrogen, to be substituted, or an acyl radical, are antibacterial agents with a broad antibacterial spectrum and are useful as agents for promoting growth and for improving feed utilization in animals and as antioxidants.