Morpholines
US4387097A · kind A · utility
2Cited by
0References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 1982 |
| Grant date | Jun 7, 1983 |
| Priority date | — |
| Expiry date | Mar 11, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D303/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Morpholine derivatives of the formula ##STR1## and their acid addition salts, wherein n represents 1, 2 or 3, R.sup.4 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, aryl(lower)alkyl, 2-tetrahydrofurylmethyl or cyclo(lower)alkylmethyl, R.sup.2 and R.sup.3 are each hydrogen or alkyl of 1 to 10 carbon atoms and OR.sup.5 is hydroxy, acyloxy or a protected hydroxy group possess analgesic and/or opiate antagonistic activity or are useful as intermediates for other compounds of formula I possessing such activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.