1-Aroyl-2-phenylamino-2-imidazolines, drugs containing these compounds, and use thereof

US4389403A · kind A · utility

Assignee

• BASF SE

Inventors

• Hans-Joachim May · Neustadt, DE
• Dieter Lenke · Ludwigshafen, DE
• Josef Gries · Monsheim, DE
• Hans-Juergen Teschendorf · Dudenhofen, DE
• Wolfgang Worstmann · Havelsee, DE

Key dates

• Filing date: Mar 3, 1981
• Grant date: Jun 21, 1983
• Expiry date: Mar 3, 2001

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

1-Aroyl-2-phenylamino-2-imidazolines of the general formula ##STR1## where R.sup.1 and R.sup.2 are identical or different and each is chlorine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano, PA1 R.sup.3 has the meanings given for R.sup.1 and R.sup.2 or is hydrogen and PA1 Ar is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds. The compounds have, inter alia, a blood pressure-reducing action.