Intermediates and synthesis of 2-amino-2-deoxytetritols
US4389526A · kind A · utility
1Cited by
8References
9Claims
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Key dates
| Filing date | Aug 3, 1981 |
| Grant date | Jun 21, 1983 |
| Priority date | — |
| Expiry date | Aug 3, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D321/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel methods are provided for synthesizing 2-amino-2-tetritol, by positive halogen addition to protected 1,4-dioxybutene-2 in the presence of a nitrile, resulting in addition of a halo functionality and the nitrile functionality across the double bond. Upon hydrolysis, the desired erythro-product can be obtained in stereochemically good yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.