Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease
US4390541A · kind A · utility
4Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 3, 1981 |
| Grant date | Jun 28, 1983 |
| Priority date | — |
| Expiry date | Dec 3, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the following formula are described: ##STR1## in which n is 0, 1 or 2, R.sup.1 is C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkylthio, C.sub.1-4 alkylsulphonyl, trifluoromethyl, halo or nitro, and R.sup.2 and R.sup.3 are each independently hydrogen or C.sub.1-4 alkyl, and salts thereof. The compounds are useful in the treatment of immediate hypersensitivity conditions and are prepared by reaction of the appropriate formylquinolone with malonic acid, ylid or phosphonate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.