Process for the ortho-alkylation of phenolic compounds
US4390737A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 30, 1981 |
| Grant date | Jun 28, 1983 |
| Priority date | — |
| Expiry date | Oct 30, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C37/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a process for the selective ortho-alkylation of a phenolic compound having at least one ortho-positioned hydrogen atom by catalytically reacting the phenolic compound with an alcohol in the vapor phase. In this process, the reaction of the phenolic compound with the alcohol is carried out at a temperature of from 300.degree. to 550.degree. C. in the presence of a catalyst containing manganese oxide, silicon oxide and one or more additives selected from group (A) consisting of germanium oxide, tin oxide and lead oxide, or a catalyst containing manganese oxide, silicon oxide, one or more additives selected from the aforesaid group (A), and one or more additives selected from group (B) consisting of alkali metal oxides and alkaline earth metal oxides. The catalyst used in this invention exhibits not only excellent catalytic activity in the selective ortho-alkylation of phenols, continuous stability of the activity, good shapability, and good mechanical strength but also effective utilization of alcohols.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.