7-Substituted benzopyranes and process for the preparation thereof
US4391821A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1981 |
| Grant date | Jul 5, 1983 |
| Priority date | — |
| Expiry date | Jul 17, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel 7-substituted benzopyranes of formula (I), wherein PA0 R.sub.1 and R.sub.2 are hydrogen, alkyl of from 1 to 6 carbon atoms, hydroxyalkyl, alkenyl, cycloalkyl, phenylalkyl, dimethoxy-phenylalkyl, or R.sub.1 and R.sub.2 together with the joining nitrogen atom may represent a 5-7-membered heterocyclic ring, PA0 R.sub.3 is hydrogen, alkyl of from 1 to 4 carbon atoms or phenyl, PA0 R.sub.4 is hydrogen, PA0 R.sub.5 is hydrogen or phenyl, or PA0 R.sub.4 and R.sub.5 together may represent a bonding electron pair between the second and the third carbon atoms of the benzopyrane ring, PA0 R.sub.6 and R.sub.7 are hydrogen or they may represent an oxygen atom together, PA0 n is 1 or 2, with the proviso, that the pyrane ring may bear only one alkyl or phenyl substituent, and preparation process thereof. The novel compounds have valuable therapeutical effects, mainly in cardiotherapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.