Preparation of 2-aminopyridine derivatives

US4395555A · kind A · utility

Assignee

• BASF SE

Inventors

• Rolf-Dieter Acker · Leimen, DE
• Gerhard Hamprecht · Weinheim, DE

Key dates

• Filing date: Jan 8, 1982
• Grant date: Jul 26, 1983
• Expiry date: Jan 8, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/85
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

2-Aminopyridine derivatives are prepared by reacting a quaternary ammonium compound with malodinitrile in the presence of an alkanol, followed by reaction with ammonia in the presence of an alkanol, water and/or an ether to give aminonicotinonitrile and, if desired, then reacting this product with an alkali metal compound to give aminonicotinic acid. The 2-aminopyridine derivatives obtainable by the process of the invention are valuable starting materials for the preparation of pesticides, drugs, vitamins and dyes.