Method of treating androgen-related disorders
US4396615A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1981 |
| Grant date | Aug 2, 1983 |
| Priority date | — |
| Expiry date | Jun 24, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/57
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating androgen-related disorders in an animal which comprises administering to the animal dihydrotestosterone level decreasing amounts of a compound of formula (I): ##STR1## wherein R is H or F; R.sup.1 is selected from the group consisting of --H; straight or branched chain lower alkyl; hydroxyl; --OCOR.sup.3 ; and O--(C.sub.1 -C.sub.6 alkyl); wherein R.sup.3 is --H, C.sub.1 -C.sub.10 straight or branched chain alkyl group, phenyl, phenyl alkylene having straight or branched chain C.sub.1 -C.sub.6 alkylene, C.sub.5 -C.sub.10 cycloalkyl or C.sub.6 -C.sub.10 cycloalkyl alkylene; R.sup.2 is H.sub.2, methylene, ethylidene, .alpha.-CH.sub.3 (H), .beta.-CH.sub.3 (H), .alpha.-(OH)(H) or the acetonide derived from the 16.alpha.,17.alpha.-dihydroxy derivative, and n is 1 or 2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.