Compositions, processes and method
US4396629A · kind A · utility
2Cited by
9References
31Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 29, 1980 |
| Grant date | Aug 2, 1983 |
| Priority date | — |
| Expiry date | Dec 29, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C381/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Therapeutically useful 1-(substituted-amino)-3-[4-R.sub.1 O-3-(lower-alkylthio, lower-alkylsulfinyl or lower-alkylsulfonyl)phenoxy]-2-propanols are obtained by reacting a 4-R.sub.1 0-3-(lower-alkylthio, lower-alkylsulfinyl or lower-alkylsulfonyl)phenol with an epihalohydrin and reacting the resulting product with a primary amine. The compounds have both antihypertensive and .beta.-adrenergic blocking activity and are useful as antihypertensive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.