Patent · US Expired

Liquid handling apparatus

US4399362A · kind A · utility

87Cited by
4References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 1981
Grant dateAug 16, 1983
Priority date
Expiry dateFeb 27, 2001

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N35/08
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A clinical analyzer system flows a small volume (less than 200 microliters) of liquid sample to be analyzed from an inlet port past a sensor array to a series of analysis chambers. The sensor array includes two optical sensor units that are spaced a fixed distance apart, and each sensor unit transmits a beam of infrared radiation through the flow tube for sensing by a detector. Each detector output has a low value when blood is in the flow tube, an intermediate value when air is in the flow tube, and a high value when a clear liquid is in the flow tube. Control logic senses changes in the outputs of the detectors and accurately indicates gas-liquid interface transitions. The noninvasive system accurately locates leading and trailing edges of samples of biological fluids to be analyzed, monitors the integrity of those samples, and distinguishes between types of sample liquids processed by the analyzer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.