Muramyl-peptides fixed to peptide-polymers and pharmaceutical compositions containing them
US4401659A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 1980 |
| Grant date | Aug 30, 1983 |
| Priority date | — |
| Expiry date | Jan 14, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/29
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A polymer of peptidic type formed by a chain formed from aminoacyl residues preferably derived of at least one of the amino-acid residues selected from the class consisting of .alpha.,.gamma.-diaminobutyric acid, ornithine, lysine, homo-lysine, of which the lateral amino functions portionally carry peptide branches of which the aminoacyl residues are preferably derived of those selected from the class consisting of alanine, glycine, .alpha.-aminobutyric acid, valine, leucine and proline, the above-said peptide polymer having an average molecular weight comprised between about 50,000 and 250,000, and to which are bound covalently, muramyl-peptide units of which the two first aminoacid residues bound to the muramyl group are stereoisomers of the D series, the second aminoacid residue having the structure of the glutamic acid. This product is useful as anti-infectious agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.