Derivatives of 1-(2-,3- or 4-quinolyl)-2- or -3-(2- or 3-piperidyl or -pyrrolidinyl) ethanone or propanone, and their utilization as antiarrhythmics, anticonvulsivants and for the treatment of anxiety
US4402961A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1981 |
| Grant date | Sep 6, 1983 |
| Priority date | — |
| Expiry date | Jun 9, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds, useful as medicaments, of the formula: ##STR1## in which R is fixed in position 2 or 4 on the cycle of the quinoline and indicates a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms, pyridyl, thienyl, phenyl or substituted phenyl group, X is fixed in position 5, 6, 7 or 8 on the cycle of the quinoline and indicates a hydrogen or halogen atom or an alkyl, alkoxy or alkylthio group containing 1 to 4 carbon atoms or CF.sub.3 group, R.sub.1 is a hydrogen atom or an alkyl containing 1 to 4 carbon atoms, alkenyl containing 3 to 4 carbon atoms or arylalkyl group, A is a CO, CHOH, or CH.sub.2 group, n and p are equal to 1 or 2, the group ##STR2## is fixed in position 2, 3 or 4 on the cycle of the quinoline and the group ##STR3## is fixed in position 2 or 3 on the nitrogen heterocycle ##STR4##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.