Gastro-protecting activity of substituted derivatives of 4-phenyl-4-oxo-2-hydroxy-butanoic acid
US4402978A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 23, 1981 |
| Grant date | Sep 6, 1983 |
| Priority date | — |
| Expiry date | Apr 23, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C205/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Diseases and ailments accompanied by gastric and gastroduodenal lesions treated by administering a compound of the formula (I) ##STR1## in which R represents hydrogen or alkyl containing 1 to 5 carbon atoms and R.sub.1 and R.sub.2, identical or different, both represent alkoxy containing 1 to 3 carbon atoms, or both represent halogen, or R.sub.1 represents hydrogen and R.sub.2 represents halogen, nitro or trifluoromethyl, or R.sub.1 and R.sub.2 form a methylenedioxy group at adjacent carbon atoms, in their racemic and optically active forms, as well as pharmaceutically acceptable salts thereof, particularly alkali metal, alkaline earth metal, or amine salts of said acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.