Process for the preparation of 7.alpha.-methoxy-7.beta.-(1,3-diethietane-2-carboxamido)cephalosporanic acid derivatives
US4404373A · kind A · utility
9Cited by
8References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1980 |
| Grant date | Sep 13, 1983 |
| Priority date | — |
| Expiry date | Nov 19, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D339/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel 7.alpha.-methoxycephalosporin derivatives having at the 7.beta.-position an amido group acylated by a 1,3-dithietane carboxylic acid residue and to 7.beta.-isothiazolylthioacetamido-7.alpha.-methoxycephalosporins having antibacterial activity by themselves and, as the case may be, capable of being converted into the aforesaid 7.alpha.-methoxycephalosporin derivatives. The compounds of this invention exhibit excellent antibacterial activity and are particularly effective against gram negative bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.