Medicament capsules for rectal application
US4405597A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 11, 1981 |
| Grant date | Sep 20, 1983 |
| Priority date | — |
| Expiry date | Aug 11, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/025
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a novel means for the administration of a therapeutically effective ingredient in the form of a rectally applicable medicament capsule, in which the otherwise unavoidable extreme variation in the absorbability of the effective ingredient among the individuals rectally treated with the capsules is minimized. It has been unexpectedly found that, when the effective ingredient is contained in the capsule in the form of a liquid medicine, the osmotic pressure of the liquid content plays a very essential role in the absorption of the effective ingredient through the rectum and the variation in the absorbability of the effective ingredient among the individuals can be minimized when the osmotic pressure of the liquid content is substantially higher than the osmotic pressure of the rectal fluid with which the capsules are contacted.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.