Aminocyclopentane esters and pharmaceutical formulations
US4410521A · kind A · utility
3Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 16, 1982 |
| Grant date | Oct 18, 1983 |
| Priority date | — |
| Expiry date | Sep 16, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds are described of the formula ##STR1## in which --COR.sup.1 is a complex ester or thioester group, PA1 W is alkylene, PA1 X is cis or trans --CH.dbd.CH or --CH.sub.2 CH.sub.2 --, PA1 n is 1 or 2, PA1 Y is a saturated heterocyclic amino group having 5-8 ring members, and PA1 R.sup.2 is unsubstituted or substituted phenylalkyl, thienylalkyl, naphthylalkyl or cinnamyl, PA1 and their salts and solvates. These compounds inhibit blood platelet aggregation and bronchoconstruction and may be formulated for use as antithrombotic and antiasthmatic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.