Patent · US Expired

Preparation of 4-hydroxyquinolines

US4412076A · kind A · utility

2Cited by

1References

9Claims

0Family size

Assignee

Rhone-Poulenc Sante · FR

Inventors

Michel Baudouin · Craponne, FR
Daniel Michelet · Saint-Nom-la-Bretèche, FR

Key dates

Filing date	Jan 15, 1982
Grant date	Oct 25, 1983
Priority date	—
Expiry date	Jan 15, 2002

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D215/233
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Process for the preparation of 4-hydroxyquinolines of the general formula: ##STR1## in which R represents a hydrogen atom, or one, two or three substituents, which may be the same or different, selected from halogen atoms, alkyl radicals containing 1 to 4 carbon atoms, alkoxy radicals containing 1 to 4 carbon atoms, and the trifluoromethyl radical, the substituent(s) being in the 2-, 3-, 5-, 6-, 7- or 8-position, by the oxidation, by means of oxygen or air, in the presence of a catalyst based on platinum or ruthenium, or alloys thereof, of a 1,2,3,4-tetrahydroquinolin-4-one of the general formula: ##STR2## in which R is as defined above.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.