Patent · US Expired

Pentacyclic phenylpyrazole compounds as anti-inflammatory agents

US4412995A · kind A · utility

4Cited by
0References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 13, 1982
Grant dateNov 1, 1983
Priority date
Expiry dateJan 13, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D231/54
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## where R is hydrogen, methyl, ethyl, propyl, 2-propenyl or 2-propynyl; and R' is hydrogen or fluoro possess anti-inflammatory activity. The compounds where R is H are prepared by reacting a compound of the formula ##STR2## with (1H,3H)-pyrimidine-2,4,5,6-tetrone. The compounds where R is other than hydrogen are prepared by reacting a compound where R is hydrogen with the appropriate alkylating agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.