Patent · US Expired

Diagnostic agents

US4414326A · kind A · utility

15Cited by
8References
8Claims
0Family size

Inventor

Key dates

Filing dateFeb 4, 1982
Grant dateNov 8, 1983
Priority date
Expiry dateFeb 4, 2002

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/81
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Diagnostic agents are described for determining high density lipoprotein cholesterol in body fuids such as serum or plasma. One is an enzymatic reagent for quantitative analysis for cholesterol composed of cholesterol oxidase, cholesterol esterase, peroxidase, 4-amino-antipyrine, a phenol or phenol derivative, a surfactant, such as sodium cholate and a polyglycol of molecular weight from about 190 to 1000, buffered to pH 5.5 to 7.8 in water. The other is a single, stable precipitating agent for lipoproteins in body fluids, comprising a bivalent metal salt of a monobasic acid, such as magnesium chloride and a water-soluble polyanion, such as sodium phosphotungstate in water at pH 5 to 8.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.