Process for producing a highly concentrated aqueous acrylamide solution by means of microorganisms
US4414331A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 1980 |
| Grant date | Nov 8, 1983 |
| Priority date | — |
| Expiry date | Jun 19, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/872
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for producing acrylamide from acrylonitrile by utilizing a microorganism or enzyme capable of hydrating acrylonitrile into acrylamide in the form of a highly concentrated aqueous solution of acrylamide which comprises bringing acrylonitrile in contact with the microorganism or enzyme in an aqueous medium at a pH of from 6 to 10, at a temperature of from the freezing point to 50.degree. C., and under such conditions that the concentration of acrylamide in the reaction solution after the completion of the reaction is from 5% by weight to less than 20% by weight, and concentrating the resulting reaction solution; this invention further includes an embodiment wherein the reaction solution is concentrated by cooling the reaction solution after the reaction to from -4.degree. C. to -9.degree. C. to crystallize ice, separating the ice, and using the ice so separated for cooling during the hydration reaction. In addition, this invention includes an embodiment wherein the concentrated solution obtained by the above embodiment is further concentrated by evaporating the water contained in the concentrated solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.