Method of preparing tissue thromboplastin

US4416812A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Udo Becker · Heiligkreuzsteinach, DE
• Eugen Schaich · Weilheim, DE
• Manfred Weigert · Tutzing, DE

Key dates

• Filing date: Dec 1, 1982
• Grant date: Nov 22, 1983
• Expiry date: Dec 1, 2002

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/839
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A tissue thromboplastin preparation which is sensitive to coagulation factor VII, is prepared from acetone dry powder mammalian tissue, by extraction with a salt solution containing 1 to 20 mmol/1 of calcium ions and, if desired, a surface active agent, after which the extract maybe dried.