Patent · US Expired

Protection of lyophilized betalactams from color formation

US4418058A · kind A · utility

13Cited by
2References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 12, 1981
Grant dateNov 29, 1983
Priority date
Expiry dateJun 12, 2001

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A stable preparation of a lyophilized .beta.-lactam antibacterial containing a 7.beta.-(.alpha.-carboxy-.alpha.-arylacetamido)-7.alpha.-methoxy-3-heteroc yclic thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid (I) alkali metal salt as the antibacterial component and a sugar or sugar alcohol compound as the stabilizing agent. ##STR1## (wherein Ar is a p-hydroxyaryl group and PA1 Het is a heterocyclic group optionally substituted by an alkyl group)

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.