Multilayer enzyme electrode membrane
US4418148A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 5, 1981 |
| Grant date | Nov 29, 1983 |
| Priority date | — |
| Expiry date | Nov 5, 2001 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/3271
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A contiguous multilayer membrane for use with an electrochemical sensor is prepared comprising a first relatively nonporous dense polymer layer, a second polymer layer less dense and more porous than the first layer, a third layer containing an enzyme and a fourth polymer layer less dense and more porous than the first layer. The polymer is preferably cellulose acetate and the second and fourth layers are prepared with a solvent and nonsolvent for the polymer. The membrane may contain multiple enzyme layers separated by a polymer layer. The multilayer membrane provides advantages of higher substrate conversion, homogeneous distribution of enzyme and/or minimized interference with analyte diffusion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.