Anthracyclinone trisaccharide compounds
US4418192A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 20, 1982 |
| Grant date | Nov 29, 1983 |
| Priority date | — |
| Expiry date | Apr 20, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are novel anthracyclinone glycosides represented by the chemical formula ##STR1## wherein R.sup.1 is hydrogen or methyl; PA1 R.sup.2 is hydrogen or hydroxyl; PA1 R.sup.3 is hydrogen or methoxycarbonyl; PA1 R.sup.4 is two hydrogen atoms or an oxygen atom; PA1 R.sup.5 is hydrogen, hydroxyl or --OCOX (wherein X is lower alkyl or aralkyl); PA1 R.sup.6 is amino, monomethylamino or dimethylamino; PA1 R.sup.7 is hydrogen or acetyl; and PA1 R.sup.8 is hydrogen or L-cinerulose A ##STR2## but, when R.sup.1 and R.sup.3 are hydrogen and methoxycarbonyl respectively, R.sup.2 is hydrogen; R.sup.4 is two hydrogen atoms; R.sup.5 is hydrogen; R.sup.6 is amino, monoethylamino or dimethylamino; R.sup.7 is acetyl; and R.sup.8 is L-cinerulose A, and their acid addition salts and a method for preparation thereof which consists of treating O-alpha-L-cinerulosyl-(1.fwdarw.4)-O-(3-O-acetyl-2-deoxy-alpha-L-fucosyl)- (1.fwdarw.4)-alpha-L-rhodosamine with corresponding aglycones.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.