Interferon inducer, a process for producing the same and pharmaceutical composition containing the same
US4419349A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1981 |
| Grant date | Dec 6, 1983 |
| Priority date | — |
| Expiry date | May 22, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K36/535
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An interferon inducer isolated from the plant tissue, having an elemental analysis of H: 8.5-8.7 %, C: 48.8-49 %, N: 6.3-6.5 % and P: 1.0-1.1 % and a molecular weight of from about 100,000 to about 3,000,000 (mainly about 200,000 to about 1,000,000) and containing as main constituents amino acids, sugars and phosphoric acid. This substance is believed to be a homogeneous polymer of protein and sugars, containing phosphoric acid. This substance has an excellent interferon inducing activity and low toxicity and is significantly active against various viruses. The interferon inducer may be produced by extracting a substance having interferon inducing activity from the tissue of a plant of the genus Perilla of the family Labiatae or a variant thereof containing said active substance and recovering the active substance from the extract thereby obtained. Preferably, the extraction may be effected with water and the recovery may be effected by ultrafiltration. Pharmaceutical composition of this invention comprises as active ingredient the interferon inducer of this invention in association with a pharmaceutical carrier or excipient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.