Novel oximes
US4420478A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1979 |
| Grant date | Dec 13, 1983 |
| Priority date | — |
| Expiry date | Apr 9, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/587
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel syn isomers of oximes of 3-azidomethyl-7-amino-thiazolyl-cephalosporanic acids of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, unsaturated alkyl of 2 to 4 carbon atoms, benzoyl and --(CH.sub.2).sub.n --R.sub.1, n is an integer from 1 to 4, R.sub.1 is selected from the group consisting of NH.sub.2 and --COOA' and A' and A are selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, magnesium, --NH.sub.4, an easily cleavable ester group and a non-toxic, pharmaceutically acceptable organic amine and their non-toxic, pharmaceutically acceptable acid addition salts having antibiotic activity and a novel process and novel intermediates for their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.