Patent · US Expired

1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]

US4420485A · kind A · utility

22Cited by
10References
37Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 29, 1982
Grant dateDec 13, 1983
Priority date
Expiry dateSep 29, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D261/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to 1'-[3-(1,2-benzisoxazol-3-yl)propyl]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines] of the formula: ##STR1## where X and Y are the same or different and are hydrogen, halogen, lower alkoxy, lower alkyl, nitro, hydroxyl and CF.sub.3 ; and n is an integer of 1 or 2; m is an integer of 2 or 3; and the sum of m and n is 3 or 4; and the pharmaceutically acceptable acid addition salts thereof. These compounds are useful as antihypertensive agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.