Contraceptive method
US4423069A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 20, 1982 |
| Grant date | Dec 27, 1983 |
| Priority date | — |
| Expiry date | Jan 20, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Contraceptive method comprises maintaining in the genital tract of a mammal an ester of 4-guanidinobenzoic acid and certain substituted phenols in a concentration effective to inhibit the fertilization of ova. In addition to effectively inhibiting the enzymes necessary for conception, the compounds used in the method of the invention are advantageous in possessing low toxicity. Further, the phenolic materials which may be liberated on hydrolysis of the 4-guanidinobenzoates in the genital tract of the animal are low in toxic, caustic or irritating properties, so that the contraceptive compositions are suitable for long-term use without adverse side-effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.