Process for heat treatment of aqueous solution containing cold insoluble globulin to inactivate hepatitis virus
US4424206A · kind A · utility
17Cited by
2References
17Claims
0Family size
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Key dates
| Filing date | Feb 22, 1982 |
| Grant date | Jan 3, 1984 |
| Priority date | — |
| Expiry date | Feb 22, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Cold insoluble globulin which may have hepatitis virus activity can be virus-inactivated with keeping at a minimum the damage of the cold insoluble globulin by heating its aqueous solution at 50.degree. to 80.degree. C. for 5 to 20 hours in the presence of 10% (W/V) or more of at least one principal stabilizer of neutral amino acids, monosaccharides, disaccharides, and sugar alcohols with or without 10% (W/V) or more of at least one auxiliary stabilizer of salts of hydrocarbon carboxylic acids or hydroxyhydrocarbon carboxylic acids both having 3 to 10 carbon atoms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.