9-Thiomaytansinoids and their pharmaceutical compositions and use
US4424219A · kind A · utility
288Cited by
8References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 3, 1982 |
| Grant date | Jan 3, 1984 |
| Priority date | — |
| Expiry date | May 3, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to 9-thiomaytansinoid compounds represented by the formula ##STR1## wherein R is hydrogen or acyl derived from a carboxylic acid, X is chlorine or hydrogen, Y is hydrogen, lower alkylsulfonyl, or alkyl or aralkyl which are unsubstituted or substituted, and methods of producing the same. The compounds are useful as antitumor, antiprotozoal and antifungal agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.