Triazolobenzodiazepine derivatives
US4427590A · kind A · utility
9Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 1971 |
| Grant date | Jan 24, 1984 |
| Priority date | — |
| Expiry date | Nov 17, 1991 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the class of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-lower alkanols, and their ethers and esters, 1-(fluoro-lower alkyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines and the 5-oxides and pharmaceutically acceptable acid addition salts thereof have central depressant properties, in particular antiaggressive and anticonvulsant actions, and are active ingredients for pharmaceutical compositions. Specific embodients are 6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-methanol and 1-(fluoromethyl)6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.