Process for making phosphonic acid ester chlorides

US4427603A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Jurgen Grosse · Hürth, DE
• Werner Pieper · Kerpen, DE

Key dates

• Filing date: May 18, 1982
• Grant date: Jan 24, 1984
• Expiry date: May 18, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/425
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The disclosure relates to a process for making phosphonic acid ester chlorides of the general formula (I) EQU R--P(O) ClOR' (I) in which R stands for an alkyl group with 1 to 6 carbon atoms or an aryl group and R' stands for an alkyl group with 1 to 20 carbon atoms or an aryl group. More particularly, a compound of general formula (II) EQU R--PCl.sub.2 (II) is reacted with a sulfuric acid monoester of general formula (III) EQU R'--O--SO.sub.3 H (III) R and R' in formulae (II) and (III) having the meanings given above; the reactants are used in about equimolar proportions and the reaction is effected at a temperature of from -20.degree. C. to 50.degree. C. After termination of the reaction, the phosphonic acid ester chloride is separated from the reaction mixture by subjecting this latter to distillation under vacuum.