Dipyridamole-containing pharmaceutical form

US4427648A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Rolf-Stefan Brickl
• Peter Gruber · Bottmingen, CH
• Gottfried Schepky · Biberach, DE
• Gerhard Bozler · Biberach, DE

Key dates

• Filing date: Jun 17, 1982
• Grant date: Jan 24, 1984
• Expiry date: Jun 17, 2002

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to vehicles for the administration of dipyridamole. More specifically, this invention relates to a method of treating cardiovascular disorders in a host in need of such treatment which comprises administering to said host a cardiovascularly effective amount of a composition comprised of (i) dipyridamole or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 5 acid equivalents to 1 mol of dipyridamole, preferably in the form of particles having particle sizes of from about 0.1 to 2.0 mm.