Muramyl peptide substituted on a peptide nitrogen and medicaments containing the same
US4427659A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 6, 1982 |
| Grant date | Jan 24, 1984 |
| Priority date | — |
| Expiry date | Jan 6, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to novel compounds of the muramyl-peptide type and to their uses. The muramyl-peptides according to the invention comprise at least two aminoacyl residues in the peptide chain, the second of these aminoacyl residues being D-glutamyl, and they are characterized in that the nitrogen of the first amino-acyl, and forming part of the pepetide linkage connecting the muramyl group to the peptide residue, is substituted by an alkyl group. These compounds are useful notably for the preparation of pharmaceutical compositions, in particular by reason of their regulatory properties on the immune responses of the organism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.