Process for the preparation of primary mono- and diamines from oxo compounds

US4429157A · kind A · utility

Inventors

• Josef Disteldorf · Herne, DE
• Werner Hubel · Herne, DE
• Lothar Broschinski · Werl, DE

Key dates

• Filing date: Jun 10, 1981
• Grant date: Jan 31, 1984
• Expiry date: Jun 10, 2001

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D211/58
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Primary amines and/or diamines can be prepared from oxo compounds, optionally containing additional reducible groups, by a process comprising: PA1 (1) reacting the oxo compound with ammonia in the presence of an imine-forming catalyst, preferably an ion exchanger loaded with ammonia ions, at a temperature of 10.degree. to 120.degree. C. and a pressure of 1 to 300 bar, whereby a Schiff base is formed; and PA1 (2) reducing the Schiff base by reaction with ammonia and hydrogen in the presence of a hydrogenation catalyst.