Substituted 1-azaspiro[4,5]decanes and their analgesic compositions
US4430335A · kind A · utility
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52Claims
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Assignee
Inventors
Key dates
| Filing date | Feb 9, 1983 |
| Grant date | Feb 7, 1984 |
| Priority date | — |
| Expiry date | Feb 9, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/54
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to substituted 1-azaspiro[4.5] decanes and 1-azaspiro[5.5]undecanes of the formula ##STR1## wherein R.sub.1 is hydrogen, --CO.sub.2 R.sub.4, R.sub.4 ; R.sub.2 is hydrogen, ##STR2## R.sub.3 is hydrogen, ##STR3## R.sub.4 is alkyl of 1 to 4 carbon atoms; R.sub.5 is alkyl of 1 to 8 carbon atoms; X is halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF.sub.3, and OH; m is an integer of 0, 1 or 2; and n is an integer of 1 or 2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.