Method of use of enantiomers of trans-indeno[1,2-b]-1,4-oxazines
US4431647A · kind A · utility
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2Claims
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Key dates
| Filing date | Aug 2, 1982 |
| Grant date | Feb 14, 1984 |
| Priority date | — |
| Expiry date | Aug 2, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/71
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The (R,R)-enantiomers of trans-indeno[1,2-b]-1,4-oxazines demonstrate dopaminergic activity, whereas the (S,S)-enantiomers demonstrate .alpha.-adrenergic antagonist activity. They are prepared by cyclization of the appropriate chiral 2-amino-1-hydroxyindane.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.