DNA Transfer vector and transformed microorganism containing human proinsulin and pre-proinsulin genes
US4431740A · kind A · utility
36Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 1982 |
| Grant date | Feb 14, 1984 |
| Priority date | — |
| Expiry date | Jun 8, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A DNA having a base sequence coding for human proinsulin and a DNA having a base sequence coding for human pre-proinsulin have been cloned, and novel recombinant DNA transfer vectors containing said cloned DNAs have been constructed. Novel microorganisms transformed by said recombinant transfer vectors have been obtained. Certain of said transformed microorganisms have demonstrated capability to express the cloned DNA's, synthesizing a protein comprising human proinsulin and a protein-comprising human pre-proinsulin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.