Compressed tablets for disintegration in the colon comprising an active ingredient containing nucleus coated with a first layer containing microcrystalline cellulose which is coated with an enteric organic polymer coating
US4432966A · kind A · utility
103Cited by
22References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 31, 1982 |
| Grant date | Feb 21, 1984 |
| Priority date | — |
| Expiry date | Aug 31, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2886
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Coated compressed tablets for oral administration are disclosed which substantially desintegrate specifically at the level of the colon. The tablets comprise a compressed center piece containing an active agent which center piece is coated by a first coating layer which is comprised of a mixture of a pharmaceutically acceptable film-forming organic polymer material which is non-deteriorated by a neutral or alkaline aqueous medium and microcrystalline cellulose and a second coating layer which is comprised of a pharmaceutically acceptable enteric organic polymer coating material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.