Methods for preparation of HB.sub.s Ag free gamma globulins
US4434093A · kind A · utility
19Cited by
15References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 26, 1982 |
| Grant date | Feb 28, 1984 |
| Priority date | — |
| Expiry date | Jul 26, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/83
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Methods for producing from human serum, human gamma globulin essentially free of HB.sub.s Ag and products resulting therefrom. Specifically provided are ion exchange resin/buffer systems capable of effectively removing HB.sub.s Ag thought to be closely correlated with viral hepatitis type B infectivity. Additional steps can include ultrafiltration to increase reduction of any virus not removed in the column passage as well as the addition of anti-HB.sub.g to substantially eliminate all infectivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.