Patent · US Expired

Process for the production of 5-cyano-and 5-carboxamido-5H-dibenz[b,f]azepines

US4436660A · kind A · utility

1Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 14, 1982
Grant dateMar 13, 1984
Priority date
Expiry dateMay 14, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D223/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to a novel and technically advanced process for producing 5-cyano-5H-dibenz[b,f]azepine by reacting 5H-dibenz[b,f]azepine with a halocyanogen in the presence of strongly polar substances. 5-Cyano-5H-dibenz[b,f]azepine can be used as starting material for producing 5-carbamyl-10(11)-oxo-10,11-dihydro-5H-dibenz[b,f]azepine, which is known to have central-depressant, anticonvulsive and central-muscle-relaxing activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.