Process for separating porphyrins
US4436663A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 2, 1982 |
| Grant date | Mar 13, 1984 |
| Priority date | — |
| Expiry date | Aug 2, 2002 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J20/26
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for separating porphyrins, which comprises PA1 (1) adjusting the pH of the liquid phase of a culture broth containing at least two porphyrins to about 2.5 to about 4 and collecting the resulting solid containing the porphyrins, PA1 (2) either (a) preparing an acidic aqueous solution of said solid and adjusting the pH of its liquid phase left after removal of insoluble matter to about 6 to about 8 to form an aqueous solution containing the porphyrins, or (b) preparing an acid-containing lower alcohol solution of said solid, adjusting the pH of its liquid phase left after removal of insoluble matter, adding water in an amount at least twice the amount of the solution to precipitate lower alkyl esters of the porphyrins, collecting the precipitates and dissolving them in an organic solvent to form an organic solvent solution of the porphyrin esters, PA1 (3) contacting the solution obtained in (a) or (b) in step (2) with a copolymer having a surface area of at least about 700 m.sup.2 /g and derived from PA2 (i) divinylbenzene, PA2 (ii) styrene or its functional derivative, PA2 (iii) an alkenyl ester of a benzenepolycarboxylic acid represented by the following formula ##STR1## …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.