.sup.18 F-4-Fluoroantipyrine
US4436717A · kind A · utility
4Cited by
5References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 29, 1981 |
| Grant date | Mar 13, 1984 |
| Priority date | — |
| Expiry date | May 29, 2001 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The novel radioactive compound .sup.18 F-4-fluoroantipyrine having high specific activity which can be used in nuclear medicine in diagnostic applications, prepared by the direct fluorination of antipyrine in acetic acid with radioactive fluorine at room temperature and purifying said radioactive compound by means of gel chromatography with ethyl acetate as eluent is disclosed. The non-radioactive 4-fluoroantipyrine can also be prepared by the direct fluorination of antipyrine in acetic acid with molecular fluorine at room temperature and purified by means of gel chromotography with ethyl acetate eluent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.