Hydronaphthalene derivatives
US4438277A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1982 |
| Grant date | Mar 20, 1984 |
| Priority date | — |
| Expiry date | Apr 15, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C59/84
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I): ##STR1## (in which: Z represents a group of formula ##STR2## A represents a group of formula ##STR3## B represents a group of formula ##STR4## R.sup.1 represents a hydrogen atom or a methyl group; R.sup.2, R.sup.3, R.sup.4 and R.sup.6 are the same or different and each represents a hydrogen atom or an acyl group; PA1 R.sup.5 represents a carboxy group; PA1 R.sup.7 represents a hydrogen atom, an alkyl group or an acyl group; PA1 X represents a halogen atom; and PA1 the bond represents a double bond) and salts and esters of the carboxy group represented by R.sup.5 have useful anti-hypercholesteraemic activity and may be prepared from certain natural products obtainable by cultivation of microorganisms of the genera Penicillium or Monascus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.